BIOGEN INC

Ticker: BIIB CUSIP: 09062X103 Class: COM

MIDDLETON & CO INC/MA's Holding History (CIK: 0000919497)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016

Shares 6,258 Value ($000) $1,775 Avg Close $296.43 Range $268.00 - $329.83

Q3 2016

Shares 9,086 Value ($000) $2,844 Avg Close $296.18 Range $240.07 - $333.65

Q2 2016

Shares 16,836 Value ($000) $4,071 Avg Close $263.54 Range $223.02 - $292.69

Q1 2016

Shares 20,472 Value ($000) $5,329 Avg Close $264.15 Range $242.07 - $301.02

Q4 2015

Shares 19,320 Value ($000) $5,919 Avg Close $287.35 Range $254.00 - $311.65

Q3 2015

Shares 22,366 Value ($000) $6,527 Avg Close $330.23 Range $265.00 - $412.24

Q2 2015

Shares 20,944 Value ($000) $8,460 Avg Close $401.33 Range $368.88 - $432.88

Q1 2015

Shares 19,038 Value ($000) $8,039 Avg Close $394.14 Range $334.40 - $480.18

Q4 2014

Shares 18,165 Value ($000) $6,166 Avg Close $323.51 Range $290.85 - $361.93

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2016	6,258	$1,775	$296.43	$268.00 - $329.83
Q3 2016	9,086	$2,844	$296.18	$240.07 - $333.65
Q2 2016	16,836	$4,071	$263.54	$223.02 - $292.69
Q1 2016	20,472	$5,329	$264.15	$242.07 - $301.02
Q4 2015	19,320	$5,919	$287.35	$254.00 - $311.65
Q3 2015	22,366	$6,527	$330.23	$265.00 - $412.24
Q2 2015	20,944	$8,460	$401.33	$368.88 - $432.88
Q1 2015	19,038	$8,039	$394.14	$334.40 - $480.18
Q4 2014	18,165	$6,166	$323.51	$290.85 - $361.93