BIOGEN INC

Ticker: BIIB CUSIP: 09062X103 Class: COM

GREAT LAKES ADVISORS, LLC's Holding History (CIK: 0001078013)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 9,490 Value ($000) $1,670 Avg Close $163.37 Range $138.00 - $185.17

Q3 2025

Shares 9,479 Value ($000) $1,328 Avg Close $135.17 Range $121.05 - $150.28

Q2 2023

Shares 777 Value ($000) $221 Avg Close $297.86 Range $273.39 - $319.76

Q1 2023

Shares 765 Value ($000) $213 Avg Close $276.70 Range $254.80 - $295.90

Q4 2022

Shares 838 Value ($000) $232 Avg Close $282.44 Range $250.31 - $311.88

Q3 2022

Shares 885 Value ($000) $236 Avg Close $212.38 Range $193.65 - $283.44

Q2 2022

Shares 1,333 Value ($000) $272 Avg Close $204.43 Range $187.16 - $225.50

Q1 2022

Shares 116,648 Value ($000) $24,566 Avg Close $217.46 Range $192.67 - $249.00

Q4 2021

Shares 112,789 Value ($000) $27,060 Avg Close $257.12 Range $221.72 - $290.76

Q3 2021

Shares 87,631 Value ($000) $24,799 Avg Close $327.75 Range $282.64 - $372.12

Q2 2021

Shares 84,101 Value ($000) $29,121 Avg Close $302.94 Range $257.03 - $468.55

Q1 2021

Shares 98,807 Value ($000) $27,641 Avg Close $269.69 Range $238.40 - $296.38

Q4 2020

Shares 100,819 Value ($000) $24,686 Avg Close $259.08 Range $223.25 - $363.92

Q3 2020

Shares 85,185 Value ($000) $24,165 Avg Close $278.91 Range $261.87 - $312.00

Q2 2020

Shares 83,404 Value ($000) $22,315 Avg Close $300.59 Range $257.60 - $350.24

Q1 2020

Shares 115,957 Value ($000) $36,686 Avg Close $303.47 Range $262.25 - $374.99

Q4 2019

Shares 170,981 Value ($000) $50,735 Avg Close $277.46 Range $219.70 - $318.00

Q3 2019

Shares 226,874 Value ($000) $52,821 Avg Close $232.85 Range $215.78 - $246.99

Q2 2019

Shares 232,555 Value ($000) $54,388 Avg Close $230.90 Range $219.20 - $245.35

Q1 2019

Shares 233,682 Value ($000) $55,238 Avg Close $314.89 Range $216.12 - $344.00

Q4 2018

Shares 147,743 Value ($000) $44,459 Avg Close $319.14 Range $278.46 - $358.41

Q3 2018

Shares 149,318 Value ($000) $52,756 Avg Close $344.30 Range $288.13 - $388.67

Q2 2018

Shares 166,016 Value ($000) $48,184 Avg Close $281.15 Range $249.17 - $310.91

Q1 2018

Shares 195,197 Value ($000) $47,481 Avg Close $310.41 Range $259.76 - $370.57

Q4 2017

Shares 72,231 Value ($000) $23,010 Avg Close $320.80 Range $301.81 - $348.84

Q3 2017

Shares 2,827 Value ($000) $885 Avg Close $296.11 Range $269.50 - $330.00

Q2 2017

Shares 1,224 Value ($000) $332 Avg Close $264.42 Range $244.28 - $291.90

Q1 2017

Shares 1,262 Value ($000) $345 Avg Close $282.75 Range $260.50 - $301.42

Q4 2016

Shares 5,469 Value ($000) $1,551 Avg Close $296.43 Range $268.00 - $329.83

Q3 2016

Shares 7,660 Value ($000) $2,398 Avg Close $296.18 Range $240.07 - $333.65

Q2 2016

Shares 4,207 Value ($000) $1,017 Avg Close $263.54 Range $223.02 - $292.69

Q1 2016

Shares 2,785 Value ($000) $725 Avg Close $264.15 Range $242.07 - $301.02

Q4 2015

Shares 2,556 Value ($000) $783 Avg Close $287.35 Range $254.00 - $311.65

Q3 2015

Shares 2,890 Value ($000) $843 Avg Close $330.23 Range $265.00 - $412.24

Q2 2015

Shares 3,046 Value ($000) $1,230 Avg Close $401.33 Range $368.88 - $432.88

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	9,490	$1,670	$163.37	$138.00 - $185.17
Q3 2025	9,479	$1,328	$135.17	$121.05 - $150.28
Q2 2023	777	$221	$297.86	$273.39 - $319.76
Q1 2023	765	$213	$276.70	$254.80 - $295.90
Q4 2022	838	$232	$282.44	$250.31 - $311.88
Q3 2022	885	$236	$212.38	$193.65 - $283.44
Q2 2022	1,333	$272	$204.43	$187.16 - $225.50
Q1 2022	116,648	$24,566	$217.46	$192.67 - $249.00
Q4 2021	112,789	$27,060	$257.12	$221.72 - $290.76
Q3 2021	87,631	$24,799	$327.75	$282.64 - $372.12
Q2 2021	84,101	$29,121	$302.94	$257.03 - $468.55
Q1 2021	98,807	$27,641	$269.69	$238.40 - $296.38
Q4 2020	100,819	$24,686	$259.08	$223.25 - $363.92
Q3 2020	85,185	$24,165	$278.91	$261.87 - $312.00
Q2 2020	83,404	$22,315	$300.59	$257.60 - $350.24
Q1 2020	115,957	$36,686	$303.47	$262.25 - $374.99
Q4 2019	170,981	$50,735	$277.46	$219.70 - $318.00
Q3 2019	226,874	$52,821	$232.85	$215.78 - $246.99
Q2 2019	232,555	$54,388	$230.90	$219.20 - $245.35
Q1 2019	233,682	$55,238	$314.89	$216.12 - $344.00
Q4 2018	147,743	$44,459	$319.14	$278.46 - $358.41
Q3 2018	149,318	$52,756	$344.30	$288.13 - $388.67
Q2 2018	166,016	$48,184	$281.15	$249.17 - $310.91
Q1 2018	195,197	$47,481	$310.41	$259.76 - $370.57
Q4 2017	72,231	$23,010	$320.80	$301.81 - $348.84
Q3 2017	2,827	$885	$296.11	$269.50 - $330.00
Q2 2017	1,224	$332	$264.42	$244.28 - $291.90
Q1 2017	1,262	$345	$282.75	$260.50 - $301.42
Q4 2016	5,469	$1,551	$296.43	$268.00 - $329.83
Q3 2016	7,660	$2,398	$296.18	$240.07 - $333.65
Q2 2016	4,207	$1,017	$263.54	$223.02 - $292.69
Q1 2016	2,785	$725	$264.15	$242.07 - $301.02
Q4 2015	2,556	$783	$287.35	$254.00 - $311.65
Q3 2015	2,890	$843	$330.23	$265.00 - $412.24
Q2 2015	3,046	$1,230	$401.33	$368.88 - $432.88