BIOTIE THERAPIES OYJ

CUSIP: 09074D103 Class: SPONSORED ADR

ADAGE CAPITAL PARTNERS GP, L.L.C.'s Holding History (CIK: 0001165408)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015
Shares 197,300 Value ($000) $2,831 Avg Close — Range —
Q3 2015
Shares 197,300 Value ($000) $2,583 Avg Close — Range —
Q2 2015
Shares 197,300 Value ($000) $3,940 Avg Close — Range —