BLUEPRINT MEDICINES CORP

CUSIP: 09627Y109 Class: Common Stock

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q2 2025
Shares 1,894 Value ($000) $243 Avg Close — Range —
Q2 2023
Shares 3,727 Value ($000) $236 Avg Close — Range —