BRICKELL BIOTECH INC

CUSIP: 10802T105 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q2 2022
Shares 130,330 Value ($000) $16 Avg Close — Range —
Q2 2021
Shares 31,374 Value ($000) $30 Avg Close — Range —