CME GROUP INC

Ticker: CME CUSIP: 12572Q105 Class: COM

PFM Health Sciences, LP's Holding History (CIK: 0001442756)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018

Shares 219,204 Value ($000) $41,237 Avg Close $142.24 Range $131.13 - $151.59

Q3 2018

Shares 124,918 Value ($000) $21,262 Avg Close $129.10 Range $121.30 - $135.87

Q2 2018

Shares 124,955 Value ($000) $20,483 Avg Close $124.75 Range $117.42 - $133.11

Q1 2018

Shares 350,074 Value ($000) $56,621 Avg Close $121.09 Range $109.17 - $131.01

Q4 2017

Shares 392,106 Value ($000) $57,267 Avg Close $105.45 Range $97.76 - $114.72

Q4 2016

Shares 129,540 Value ($000) $14,942 Avg Close $78.61 Range $69.64 - $87.71

Q3 2016

Shares 515,625 Value ($000) $53,893 Avg Close $73.18 Range $66.90 - $77.66

Q4 2013

Shares 905,252 Value ($000) $71,026 Avg Close $47.43 Range $43.19 - $51.40

Q2 2013

Shares 212,175 Value ($000) $16,115 Avg Close $39.16 Range $34.77 - $47.64

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2018	219,204	$41,237	$142.24	$131.13 - $151.59
Q3 2018	124,918	$21,262	$129.10	$121.30 - $135.87
Q2 2018	124,955	$20,483	$124.75	$117.42 - $133.11
Q1 2018	350,074	$56,621	$121.09	$109.17 - $131.01
Q4 2017	392,106	$57,267	$105.45	$97.76 - $114.72
Q4 2016	129,540	$14,942	$78.61	$69.64 - $87.71
Q3 2016	515,625	$53,893	$73.18	$66.90 - $77.66
Q4 2013	905,252	$71,026	$47.43	$43.19 - $51.40
Q2 2013	212,175	$16,115	$39.16	$34.77 - $47.64