CADENCE PHARMACEUTICALS INC

CUSIP: 12738T100 Class: CMN

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q4 2013
Shares 48,465 Value ($000) $439 Avg Close — Range —
Q3 2013
Shares 50,333 Value ($000) $318 Avg Close — Range —
Q2 2013
Shares 51,621 Value ($000) $352 Avg Close — Range —