CALITHERA BIOSCIENCES INC

CUSIP: 13089P101 Class: Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022
Shares 845,486 Value ($000) $342 Avg Close — Range —
Q4 2021
Shares 983,221 Value ($000) $654 Avg Close — Range —
Q3 2021
Shares 200,323 Value ($000) $437 Avg Close — Range —
Q2 2021
Shares 17,700 Value ($000) $37 Avg Close — Range —
Q1 2021
Shares 85,000 Value ($000) $206 Avg Close — Range —
Q4 2020
Shares 13,600 Value ($000) $67 Avg Close — Range —
Q3 2020
Shares 200,789 Value ($000) $693 Avg Close — Range —
Q2 2020
Shares 323,299 Value ($000) $1,707 Avg Close — Range —
Q1 2020
Shares 85,218 Value ($000) $378 Avg Close — Range —
Q4 2019
Shares 142,673 Value ($000) $815 Avg Close — Range —
Q3 2019
Shares 57,057 Value ($000) $176 Avg Close — Range —
Q2 2019
Shares 81,792 Value ($000) $319 Avg Close — Range —
Q1 2019
Shares 16,550 Value ($000) $112 Avg Close — Range —
Q4 2018
Shares 43,279 Value ($000) $174 Avg Close — Range —
Q3 2018
Shares 73,417 Value ($000) $385 Avg Close — Range —
Q4 2017
Shares 29,884 Value ($000) $250 Avg Close — Range —
Q1 2017
Shares 13,730 Value ($000) $159 Avg Close — Range —