CARBYLAN THERAPEUTICS INC

CUSIP: 141384107 Class: COM

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 4,366 Value ($000) $2 Avg Close — Range —
Q2 2016
Shares 4,366 Value ($000) $3 Avg Close — Range —
Q1 2016
Shares 3,712 Value ($000) $3 Avg Close — Range —
Q4 2015
Shares 1,126 Value ($000) $4 Avg Close — Range —
Q3 2015
Shares 1,126 Value ($000) $4 Avg Close — Range —
Q2 2015
Shares 1,126 Value ($000) $8 Avg Close — Range —