CARDIOME PHARMA CORP

CUSIP: 14159U301 Class: COM NO PAR

SIMPLEX TRADING, LLC's Holding History (CIK: 0001488542)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 358 Value ($000) $0 Avg Close — Range —
Q3 2017
Shares 11,124 Value ($000) $23 Avg Close — Range —
Q2 2017
Shares 25,176 Value ($000) $113 Avg Close — Range —
Q1 2017
Shares 19,280 Value ($000) $58 Avg Close — Range —
Q4 2016
Shares 390 Value ($000) $1 Avg Close — Range —
Q3 2016
Shares 290 Value ($000) $0 Avg Close — Range —
Q2 2016
Shares 1,892 Value ($000) $9 Avg Close — Range —
Q4 2015
Shares 5,010 Value ($000) $40 Avg Close — Range —
Q3 2015
Shares 82 Value ($000) $0 Avg Close — Range —
Q2 2015
Shares 2,350 Value ($000) $22 Avg Close — Range —
Q1 2015
Shares 121 Value ($000) $1 Avg Close — Range —
Q4 2014
Shares 1,263 Value ($000) $12 Avg Close — Range —