CASSAVA SCIENCES INC

Ticker: SAVA CUSIP: 14817C107 Class: COM

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 469,326 Value ($000) $929 Avg Close $3.20 Range $1.96 - $4.98

Q3 2023

Shares 16,553 Value ($000) $275 Avg Close $19.82 Range $16.55 - $27.21

Q2 2023

Shares 13,136 Value ($000) $322 Avg Close $24.08 Range $21.45 - $28.65

Q1 2022

Shares 44,400 Value ($000) $1,649 Avg Close $42.37 Range $32.30 - $62.49

Q3 2021

Shares 49,269 Value ($000) $3,059 Avg Close $83.46 Range $39.01 - $146.16

Q2 2021

Shares 59,990 Value ($000) $5,126 Avg Close $53.57 Range $31.44 - $92.50

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	469,326	$929	$3.20	$1.96 - $4.98
Q3 2023	16,553	$275	$19.82	$16.55 - $27.21
Q2 2023	13,136	$322	$24.08	$21.45 - $28.65
Q1 2022	44,400	$1,649	$42.37	$32.30 - $62.49
Q3 2021	49,269	$3,059	$83.46	$39.01 - $146.16
Q2 2021	59,990	$5,126	$53.57	$31.44 - $92.50