CASSAVA SCIENCES INC

Ticker: SAVA CUSIP: 14817C107 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 954,800 Value ($000) $1,891 Avg Close $3.20 Range $1.96 - $4.98

Q3 2025

Shares 961,500 Value ($000) $2,798 Avg Close $2.30 Range $1.76 - $3.66

Q2 2025

Shares 983,600 Value ($000) $1,780 Avg Close $1.78 Range $1.15 - $2.32

Q1 2025

Shares 908,600 Value ($000) $1,363 Avg Close $2.52 Range $1.50 - $3.18

Q4 2024

Shares 606,700 Value ($000) $1,432 Avg Close $17.56 Range $2.23 - $33.98

Q4 2019

Shares 39,075 Value ($000) $203 Avg Close $1.73 Range $1.05 - $7.20

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	954,800	$1,891	$3.20	$1.96 - $4.98
Q3 2025	961,500	$2,798	$2.30	$1.76 - $3.66
Q2 2025	983,600	$1,780	$1.78	$1.15 - $2.32
Q1 2025	908,600	$1,363	$2.52	$1.50 - $3.18
Q4 2024	606,700	$1,432	$17.56	$2.23 - $33.98
Q4 2019	39,075	$203	$1.73	$1.05 - $7.20