CEMPRA INC

CUSIP: 15130J109 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q3 2017
Shares 14,700 Value ($000) $48 Avg Close — Range —
Q2 2017
Shares 14,700 Value ($000) $68 Avg Close — Range —
Q1 2017
Shares 14,700 Value ($000) $55 Avg Close — Range —
Q4 2016
Shares 14,700 Value ($000) $41 Avg Close — Range —
Q1 2015
Shares 45,403 Value ($000) $1,558 Avg Close — Range —
Q4 2014
Shares 31,903 Value ($000) $750 Avg Close — Range —