CHIASMA INC

CUSIP: 16706W102 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q2 2021
Shares 77,703 Value ($000) $368 Avg Close — Range —
Q1 2021
Shares 18,147 Value ($000) $57 Avg Close — Range —
Q4 2020
Shares 432,964 Value ($000) $1,883 Avg Close — Range —
Q3 2020
Shares 378,595 Value ($000) $1,628 Avg Close — Range —
Q2 2020
Shares 151,959 Value ($000) $818 Avg Close — Range —
Q4 2019
Shares 57,928 Value ($000) $287 Avg Close — Range —
Q3 2019
Shares 17,900 Value ($000) $89 Avg Close — Range —