CHIASMA INC

CUSIP: 16706W102 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 11,495 Value ($000) $17 Avg Close — Range —
Q2 2017
Shares 12,104 Value ($000) $18 Avg Close — Range —