CLENE INC

CUSIP: 185634102 Class: COMMON

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q1 2023
Shares 72,800 Value ($000) $82 Avg Close — Range —
Q4 2022
Shares 11,970 Value ($000) $12 Avg Close — Range —
Q3 2022
Shares 33,399 Value ($000) $94 Avg Close — Range —