COLLEGIUM PHARMACEUTICAL INC

Ticker: COLL CUSIP: 19459J104 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 366,099 Value ($000) $16,950 Avg Close $41.84 Range $31.26 - $50.79

Q3 2025

Shares 269,318 Value ($000) $9,423 Avg Close $34.76 Range $29.19 - $39.95

Q2 2025

Shares 27,008 Value ($000) $799 Avg Close $28.52 Range $23.23 - $30.93

Q1 2025

Shares 75,224 Value ($000) $2,245 Avg Close $30.56 Range $27.27 - $34.06

Q4 2024

Shares 70,823 Value ($000) $2,029 Avg Close $33.09 Range $28.47 - $42.29

Q3 2024

Shares 206,405 Value ($000) $7,975 Avg Close $35.66 Range $31.26 - $39.58

Q2 2024

Shares 254,773 Value ($000) $8,204 Avg Close $34.67 Range $30.42 - $40.49

Q1 2024

Shares 225,806 Value ($000) $8,766 Avg Close $34.99 Range $30.72 - $40.95

Q4 2023

Shares 259,812 Value ($000) $7,997 Avg Close $25.05 Range $20.95 - $31.12

Q3 2023

Shares 349,006 Value ($000) $7,800 Avg Close $22.81 Range $20.83 - $25.49

Q2 2023

Shares 365,622 Value ($000) $7,857 Avg Close $22.70 Range $20.93 - $24.17

Q1 2023

Shares 359,209 Value ($000) $8,617 Avg Close $26.52 Range $22.67 - $30.22

Q4 2022

Shares 113,546 Value ($000) $2,634 Avg Close $20.16 Range $15.92 - $24.36

Q1 2022

Shares 28,734 Value ($000) $585 Avg Close $18.89 Range $17.07 - $22.89

Q2 2021

Shares 41,734 Value ($000) $987 Avg Close $23.10 Range $21.27 - $25.66

Q1 2021

Shares 42,508 Value ($000) $1,007 Avg Close $23.76 Range $18.76 - $26.91

Q2 2020

Shares 112,538 Value ($000) $1,969 Avg Close $19.58 Range $15.23 - $24.32

Q1 2020

Shares 181,913 Value ($000) $2,971 Avg Close $20.64 Range $13.00 - $25.59

Q4 2019

Shares 62,936 Value ($000) $1,295 Avg Close $16.67 Range $10.43 - $22.28

Q1 2019

Shares 69,072 Value ($000) $1,046 Avg Close $16.02 Range $13.10 - $18.88

Q3 2018

Shares 228,319 Value ($000) $3,365 Avg Close $17.73 Range $14.00 - $24.44

Q1 2018

Shares 10,287 Value ($000) $263 Avg Close $23.83 Range $17.17 - $29.90

Q4 2017

Shares 63,723 Value ($000) $1,176 Avg Close $14.32 Range $9.01 - $20.92

Q4 2015

Shares 8,500 Value ($000) $234 Avg Close $21.07 Range $15.51 - $30.58

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	366,099	$16,950	$41.84	$31.26 - $50.79
Q3 2025	269,318	$9,423	$34.76	$29.19 - $39.95
Q2 2025	27,008	$799	$28.52	$23.23 - $30.93
Q1 2025	75,224	$2,245	$30.56	$27.27 - $34.06
Q4 2024	70,823	$2,029	$33.09	$28.47 - $42.29
Q3 2024	206,405	$7,975	$35.66	$31.26 - $39.58
Q2 2024	254,773	$8,204	$34.67	$30.42 - $40.49
Q1 2024	225,806	$8,766	$34.99	$30.72 - $40.95
Q4 2023	259,812	$7,997	$25.05	$20.95 - $31.12
Q3 2023	349,006	$7,800	$22.81	$20.83 - $25.49
Q2 2023	365,622	$7,857	$22.70	$20.93 - $24.17
Q1 2023	359,209	$8,617	$26.52	$22.67 - $30.22
Q4 2022	113,546	$2,634	$20.16	$15.92 - $24.36
Q1 2022	28,734	$585	$18.89	$17.07 - $22.89
Q2 2021	41,734	$987	$23.10	$21.27 - $25.66
Q1 2021	42,508	$1,007	$23.76	$18.76 - $26.91
Q2 2020	112,538	$1,969	$19.58	$15.23 - $24.32
Q1 2020	181,913	$2,971	$20.64	$13.00 - $25.59
Q4 2019	62,936	$1,295	$16.67	$10.43 - $22.28
Q1 2019	69,072	$1,046	$16.02	$13.10 - $18.88
Q3 2018	228,319	$3,365	$17.73	$14.00 - $24.44
Q1 2018	10,287	$263	$23.83	$17.17 - $29.90
Q4 2017	63,723	$1,176	$14.32	$9.01 - $20.92
Q4 2015	8,500	$234	$21.07	$15.51 - $30.58