COLLEGIUM PHARMACEUTICAL INC

Ticker: COLL CUSIP: 19459J104 Class: Common Stock

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016

Shares 486,557 Value ($000) $8,831 Avg Close $18.18 Range $13.80 - $28.47

Q4 2015

Shares 857,683 Value ($000) $23,586 Avg Close $21.07 Range $15.51 - $30.58

Q3 2015

Shares 1,553,175 Value ($000) $34,341 Avg Close $18.01 Range $12.58 - $24.88

Q2 2015

Shares 1,545,410 Value ($000) $27,570 Avg Close $17.29 Range $11.92 - $20.62

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2016	486,557	$8,831	$18.18	$13.80 - $28.47
Q4 2015	857,683	$23,586	$21.07	$15.51 - $30.58
Q3 2015	1,553,175	$34,341	$18.01	$12.58 - $24.88
Q2 2015	1,545,410	$27,570	$17.29	$11.92 - $20.62