COLLEGIUM PHARMACEUTICAL INC

Ticker: COLL CUSIP: 19459J104 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 53,000 Value ($000) $2,454 Avg Close $41.84 Range $31.26 - $50.79

Q3 2025

Shares 102,500 Value ($000) $3,586 Avg Close $34.76 Range $29.19 - $39.95

Q2 2025

Shares 21,600 Value ($000) $639 Avg Close $28.52 Range $23.23 - $30.93

Q1 2025

Shares 46,300 Value ($000) $1,382 Avg Close $30.56 Range $27.27 - $34.06

Q4 2024

Shares 72,000 Value ($000) $2,063 Avg Close $33.09 Range $28.47 - $42.29

Q3 2024

Shares 217,300 Value ($000) $8,396 Avg Close $35.66 Range $31.26 - $39.58

Q2 2024

Shares 257,900 Value ($000) $8,304 Avg Close $34.67 Range $30.42 - $40.49

Q1 2024

Shares 267,700 Value ($000) $10,392 Avg Close $34.99 Range $30.72 - $40.95

Q4 2023

Shares 245,000 Value ($000) $7,541 Avg Close $25.05 Range $20.95 - $31.12

Q3 2023

Shares 309,000 Value ($000) $6,906 Avg Close $22.81 Range $20.83 - $25.49

Q2 2023

Shares 309,600 Value ($000) $6,653 Avg Close $22.70 Range $20.93 - $24.17

Q1 2023

Shares 177,000 Value ($000) $4,246 Avg Close $26.52 Range $22.67 - $30.22

Q4 2022

Shares 42,500 Value ($000) $986 Avg Close $20.16 Range $15.92 - $24.36

Q3 2022

Shares 13,200 Value ($000) $211 Avg Close $17.63 Range $15.40 - $20.27

Q1 2022

Shares 26,700 Value ($000) $544 Avg Close $18.89 Range $17.07 - $22.89

Q4 2021

Shares 21,700 Value ($000) $405 Avg Close $19.49 Range $17.22 - $21.41

Q3 2021

Shares 29,600 Value ($000) $584 Avg Close $21.62 Range $17.67 - $25.63

Q2 2021

Shares 56,700 Value ($000) $1,340 Avg Close $23.10 Range $21.27 - $25.66

Q1 2021

Shares 85,500 Value ($000) $2,026 Avg Close $23.76 Range $18.76 - $26.91

Q3 2020

Shares 46,100 Value ($000) $960 Avg Close $18.05 Range $15.66 - $20.90

Q2 2020

Shares 110,700 Value ($000) $1,937 Avg Close $19.58 Range $15.23 - $24.32

Q1 2020

Shares 80,200 Value ($000) $1,310 Avg Close $20.64 Range $13.00 - $25.59

Q4 2019

Shares 22,700 Value ($000) $467 Avg Close $16.67 Range $10.43 - $22.28

Q2 2019

Shares 29,000 Value ($000) $381 Avg Close $13.37 Range $10.55 - $17.02

Q1 2019

Shares 27,100 Value ($000) $410 Avg Close $16.02 Range $13.10 - $18.88

Q4 2018

Shares 22,800 Value ($000) $391 Avg Close $17.11 Range $13.70 - $19.83

Q3 2018

Shares 31,000 Value ($000) $457 Avg Close $17.73 Range $14.00 - $24.44

Q2 2018

Shares 15,000 Value ($000) $358 Avg Close $24.59 Range $20.81 - $28.91

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	53,000	$2,454	$41.84	$31.26 - $50.79
Q3 2025	102,500	$3,586	$34.76	$29.19 - $39.95
Q2 2025	21,600	$639	$28.52	$23.23 - $30.93
Q1 2025	46,300	$1,382	$30.56	$27.27 - $34.06
Q4 2024	72,000	$2,063	$33.09	$28.47 - $42.29
Q3 2024	217,300	$8,396	$35.66	$31.26 - $39.58
Q2 2024	257,900	$8,304	$34.67	$30.42 - $40.49
Q1 2024	267,700	$10,392	$34.99	$30.72 - $40.95
Q4 2023	245,000	$7,541	$25.05	$20.95 - $31.12
Q3 2023	309,000	$6,906	$22.81	$20.83 - $25.49
Q2 2023	309,600	$6,653	$22.70	$20.93 - $24.17
Q1 2023	177,000	$4,246	$26.52	$22.67 - $30.22
Q4 2022	42,500	$986	$20.16	$15.92 - $24.36
Q3 2022	13,200	$211	$17.63	$15.40 - $20.27
Q1 2022	26,700	$544	$18.89	$17.07 - $22.89
Q4 2021	21,700	$405	$19.49	$17.22 - $21.41
Q3 2021	29,600	$584	$21.62	$17.67 - $25.63
Q2 2021	56,700	$1,340	$23.10	$21.27 - $25.66
Q1 2021	85,500	$2,026	$23.76	$18.76 - $26.91
Q3 2020	46,100	$960	$18.05	$15.66 - $20.90
Q2 2020	110,700	$1,937	$19.58	$15.23 - $24.32
Q1 2020	80,200	$1,310	$20.64	$13.00 - $25.59
Q4 2019	22,700	$467	$16.67	$10.43 - $22.28
Q2 2019	29,000	$381	$13.37	$10.55 - $17.02
Q1 2019	27,100	$410	$16.02	$13.10 - $18.88
Q4 2018	22,800	$391	$17.11	$13.70 - $19.83
Q3 2018	31,000	$457	$17.73	$14.00 - $24.44
Q2 2018	15,000	$358	$24.59	$20.81 - $28.91