CONATUS PHARMACEUTICALS INC

CUSIP: 20600T108 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 250,085 Value ($000) $433 Avg Close — Range —
Q3 2018
Shares 29,041 Value ($000) $168 Avg Close — Range —
Q1 2018
Shares 19,652 Value ($000) $115 Avg Close — Range —