CUE BIOPHARMA INC

Ticker: CUE CUSIP: 22978P106 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2023

Shares 27,100 Value ($000) $99 Avg Close $3.92 Range $3.03 - $5.12

Q1 2023

Shares 33,100 Value ($000) $118 Avg Close $3.18 Range $2.25 - $3.80

Q4 2022

Shares 108,900 Value ($000) $310 Avg Close $3.05 Range $2.18 - $4.19

Q3 2022

Shares 183,300 Value ($000) $409 Avg Close $2.87 Range $2.20 - $3.44

Q2 2022

Shares 214,100 Value ($000) $533 Avg Close $3.90 Range $2.46 - $6.29

Q1 2022

Shares 205,500 Value ($000) $1,003 Avg Close $7.07 Range $4.29 - $12.74

Q4 2021

Shares 227,200 Value ($000) $2,570 Avg Close $12.89 Range $10.27 - $18.42

Q3 2021

Shares 202,000 Value ($000) $2,943 Avg Close $11.63 Range $9.65 - $15.78

Q2 2021

Shares 298,000 Value ($000) $3,472 Avg Close $12.92 Range $10.69 - $15.79

Q1 2021

Shares 366,100 Value ($000) $4,466 Avg Close $13.72 Range $10.75 - $16.75

Q4 2020

Shares 350,700 Value ($000) $4,387 Avg Close $13.32 Range $10.75 - $17.23

Q3 2020

Shares 293,400 Value ($000) $4,416 Avg Close $19.21 Range $13.96 - $24.73

Q2 2020

Shares 137,600 Value ($000) $3,373 Avg Close $24.15 Range $12.08 - $31.69

Q1 2020

Shares 10,600 Value ($000) $150 Avg Close $16.16 Range $9.30 - $22.82

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2023	27,100	$99	$3.92	$3.03 - $5.12
Q1 2023	33,100	$118	$3.18	$2.25 - $3.80
Q4 2022	108,900	$310	$3.05	$2.18 - $4.19
Q3 2022	183,300	$409	$2.87	$2.20 - $3.44
Q2 2022	214,100	$533	$3.90	$2.46 - $6.29
Q1 2022	205,500	$1,003	$7.07	$4.29 - $12.74
Q4 2021	227,200	$2,570	$12.89	$10.27 - $18.42
Q3 2021	202,000	$2,943	$11.63	$9.65 - $15.78
Q2 2021	298,000	$3,472	$12.92	$10.69 - $15.79
Q1 2021	366,100	$4,466	$13.72	$10.75 - $16.75
Q4 2020	350,700	$4,387	$13.32	$10.75 - $17.23
Q3 2020	293,400	$4,416	$19.21	$13.96 - $24.73
Q2 2020	137,600	$3,373	$24.15	$12.08 - $31.69
Q1 2020	10,600	$150	$16.16	$9.30 - $22.82