CYCLERION THERAPEUTICS INC

CUSIP: 23255M105 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022
Shares 42,400 Value ($000) $47 Avg Close — Range —
Q4 2021
Shares 137,587 Value ($000) $237 Avg Close — Range —
Q3 2021
Shares 390,596 Value ($000) $1,199 Avg Close — Range —
Q2 2021
Shares 153,700 Value ($000) $599 Avg Close — Range —
Q1 2021
Shares 156,911 Value ($000) $438 Avg Close — Range —
Q4 2020
Shares 107,777 Value ($000) $330 Avg Close — Range —
Q4 2019
Shares 98,112 Value ($000) $267 Avg Close — Range —