DARE BIOSCIENCE INC

CUSIP: 23666P101 Class: COMMON

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021
Shares 155,128 Value ($000) $310 Avg Close — Range —
Q3 2021
Shares 12,739 Value ($000) $21 Avg Close — Range —
Q4 2020
Shares 29,190 Value ($000) $39 Avg Close — Range —