DIAMEDICA THERAPEUTICS INC

Ticker: DMAC CUSIP: 25253X207 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q3 2022

Shares 24,900 Value ($000) $31 Avg Close $1.56 Range $1.15 - $2.10

Q2 2022

Shares 26,700 Value ($000) $54 Avg Close $2.33 Range $1.62 - $2.71

Q1 2022

Shares 49,400 Value ($000) $124 Avg Close $2.84 Range $2.20 - $3.94

Q4 2021

Shares 106,600 Value ($000) $398 Avg Close $3.93 Range $3.28 - $4.80

Q3 2021

Shares 80,600 Value ($000) $323 Avg Close $3.83 Range $3.00 - $4.82

Q2 2021

Shares 12,800 Value ($000) $57 Avg Close $8.20 Range $4.26 - $10.28

Q1 2021

Shares 10,700 Value ($000) $98 Avg Close $9.34 Range $7.32 - $10.88

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2022	24,900	$31	$1.56	$1.15 - $2.10
Q2 2022	26,700	$54	$2.33	$1.62 - $2.71
Q1 2022	49,400	$124	$2.84	$2.20 - $3.94
Q4 2021	106,600	$398	$3.93	$3.28 - $4.80
Q3 2021	80,600	$323	$3.83	$3.00 - $4.82
Q2 2021	12,800	$57	$8.20	$4.26 - $10.28
Q1 2021	10,700	$98	$9.34	$7.32 - $10.88