DIFFUSION PHARMACEUTICALS IN

CUSIP: 253748206 Class: COM NEW

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 45,443 Value ($000) $20 Avg Close — Range —
Q2 2018
Shares 18,604 Value ($000) $9 Avg Close — Range —
Q1 2018
Shares 12,227 Value ($000) $7 Avg Close — Range —