DIFFUSION PHARMACEUTICALS IN

CUSIP: 253748305 Class: COM PAR

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022
Shares 15,457 Value ($000) $4 Avg Close — Range —
Q3 2021
Shares 13,200 Value ($000) $7 Avg Close — Range —