DURECT CORP

CUSIP: 266605104 Class: COM

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 381,800 Value ($000) $745 Avg Close — Range —
Q2 2015
Shares 381,800 Value ($000) $913 Avg Close — Range —