DURECT CORP

CUSIP: 266605104 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021
Shares 30,634 Value ($000) $30 Avg Close — Range —
Q3 2021
Shares 12,111 Value ($000) $16 Avg Close — Range —
Q1 2018
Shares 37,815 Value ($000) $81 Avg Close — Range —
Q4 2017
Shares 44,650 Value ($000) $41 Avg Close — Range —
Q3 2017
Shares 28,997 Value ($000) $51 Avg Close — Range —
Q3 2016
Shares 27,150 Value ($000) $38 Avg Close — Range —
Q2 2016
Shares 24,738 Value ($000) $30 Avg Close — Range —
Q1 2016
Shares 14,444 Value ($000) $19 Avg Close — Range —
Q1 2015
Shares 13,781 Value ($000) $26 Avg Close — Range —