ELEVEN BIOTHERAPEUTICS INC

CUSIP: 286221106 Class: CMN

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2017
Shares 65,152 Value ($000) $53 Avg Close — Range —
Q2 2017
Shares 17,489 Value ($000) $27 Avg Close — Range —
Q2 2016
Shares 25,428 Value ($000) $42 Avg Close — Range —
Q1 2016
Shares 23,434 Value ($000) $7 Avg Close — Range —