ENTASIS THERAPEUTICS HLDGS I

CUSIP: 293614103 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021
Shares 99,542 Value ($000) $218 Avg Close — Range —
Q3 2021
Shares 186,230 Value ($000) $622 Avg Close — Range —
Q2 2021
Shares 164,229 Value ($000) $438 Avg Close — Range —
Q1 2021
Shares 39,361 Value ($000) $84 Avg Close — Range —
Q4 2020
Shares 20,731 Value ($000) $51 Avg Close — Range —