EPIRUS BIOPHARMACEUTICALS IN

CUSIP: 29428P107 Class: COM

FMR LLC's Holding History (CIK: 0000315066)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 1,374,776 Value ($000) $3,698 Avg Close — Range —
Q4 2015
Shares 1,474,800 Value ($000) $4,557 Avg Close — Range —
Q3 2015
Shares 1,474,800 Value ($000) $6,519 Avg Close — Range —
Q2 2015
Shares 1,474,800 Value ($000) $8,421 Avg Close — Range —
Q1 2015
Shares 1,474,800 Value ($000) $13,199 Avg Close — Range —