EPIRUS BIOPHARMACEUTICALS IN

CUSIP: 29428P107 Class: COM

CITADEL ADVISORS LLC's Holding History (CIK: 0001423053)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 10,359 Value ($000) $28 Avg Close — Range —
Q4 2015
Shares 14,535 Value ($000) $45 Avg Close — Range —
Q2 2015
Shares 40,383 Value ($000) $230 Avg Close — Range —