EPIRUS BIOPHARMACEUTICALS IN

CUSIP: 29428P107 Class: COM

SIMPLEX TRADING, LLC's Holding History (CIK: 0001488542)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015
Shares 43,008 Value ($000) $132 Avg Close — Range —
Q3 2015
Shares 16,818 Value ($000) $74 Avg Close — Range —
Q4 2014
Shares 110 Value ($000) $1 Avg Close — Range —