EPIZYME INC

CUSIP: 29428V104 Class: COM

ADAGE CAPITAL PARTNERS GP, L.L.C.'s Holding History (CIK: 0001165408)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 403,000 Value ($000) $7,153 Avg Close — Range —
Q3 2014
Shares 100,000 Value ($000) $2,711 Avg Close — Range —
Q3 2013
Shares 313,380 Value ($000) $12,535 Avg Close — Range —
Q2 2013
Shares 325,000 Value ($000) $9,142 Avg Close — Range —