EPIZYME INC

CUSIP: 29428V104 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q2 2022
Shares 45,316 Value ($000) $67 Avg Close — Range —
Q1 2022
Shares 1,115,516 Value ($000) $1,283 Avg Close — Range —
Q4 2021
Shares 1,022,627 Value ($000) $2,557 Avg Close — Range —
Q3 2021
Shares 12,000 Value ($000) $61 Avg Close — Range —
Q1 2021
Shares 356,702 Value ($000) $3,107 Avg Close — Range —
Q3 2020
Shares 71,909 Value ($000) $858 Avg Close — Range —
Q2 2020
Shares 56,728 Value ($000) $911 Avg Close — Range —
Q1 2020
Shares 71,224 Value ($000) $1,105 Avg Close — Range —
Q3 2019
Shares 32,454 Value ($000) $335 Avg Close — Range —
Q2 2019
Shares 37,933 Value ($000) $476 Avg Close — Range —
Q1 2019
Shares 66,764 Value ($000) $827 Avg Close — Range —
Q4 2018
Shares 270,213 Value ($000) $1,665 Avg Close — Range —
Q3 2018
Shares 42,021 Value ($000) $445 Avg Close — Range —