EPIZYME INC

CUSIP: 29428V104 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022
Shares 379,300 Value ($000) $436 Avg Close — Range —
Q4 2021
Shares 315,400 Value ($000) $789 Avg Close — Range —
Q1 2021
Shares 20,800 Value ($000) $181 Avg Close — Range —
Q4 2020
Shares 19,400 Value ($000) $211 Avg Close — Range —
Q3 2020
Shares 172,200 Value ($000) $2,054 Avg Close — Range —
Q2 2020
Shares 73,100 Value ($000) $1,174 Avg Close — Range —
Q4 2018
Shares 12,400 Value ($000) $76 Avg Close — Range —