EQUILLIUM INC

Ticker: EQ CUSIP: 29446K106 Class: 0

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 324,610 Value ($000) $503 Avg Close $1.22 Range $0.76 - $1.70

Q3 2025

Shares 133,004 Value ($000) $190 Avg Close $1.06 Range $0.29 - $2.35

Q4 2022

Shares 14,464 Value ($000) $15 Avg Close $1.60 Range $0.79 - $2.34

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	324,610	$503	$1.22	$0.76 - $1.70
Q3 2025	133,004	$190	$1.06	$0.29 - $2.35
Q4 2022	14,464	$15	$1.60	$0.79 - $2.34