ESPERION THERAPEUTICS INC NE

Ticker: ESPR CUSIP: 29664W105 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,505,200 Value ($000) $12,969 Avg Close $3.23 Range $2.30 - $4.13

Q3 2025

Shares 1,908,000 Value ($000) $5,056 Avg Close $1.93 Range $0.95 - $2.94

Q2 2025

Shares 2,093,700 Value ($000) $2,061 Avg Close $1.00 Range $0.69 - $1.46

Q1 2025

Shares 2,527,000 Value ($000) $3,639 Avg Close $1.84 Range $1.42 - $2.40

Q4 2024

Shares 3,616,200 Value ($000) $7,956 Avg Close $2.33 Range $1.58 - $3.94

Q3 2024

Shares 3,600,100 Value ($000) $5,940 Avg Close $2.02 Range $1.60 - $2.77

Q2 2024

Shares 3,874,300 Value ($000) $8,601 Avg Close $2.35 Range $1.71 - $3.40

Q1 2024

Shares 3,569,700 Value ($000) $9,567 Avg Close $2.43 Range $1.65 - $3.34

Q4 2023

Shares 2,146,600 Value ($000) $6,418 Avg Close $1.30 Range $0.70 - $3.28

Q3 2023

Shares 1,536,300 Value ($000) $1,506 Avg Close $1.45 Range $0.85 - $1.99

Q2 2023

Shares 685,032 Value ($000) $952 Avg Close $1.40 Range $1.12 - $1.84

Q1 2023

Shares 857,200 Value ($000) $1,363 Avg Close $5.16 Range $1.26 - $7.41

Q4 2022

Shares 1,416,000 Value ($000) $8,822 Avg Close $7.15 Range $4.88 - $8.87

Q3 2022

Shares 1,084,300 Value ($000) $7,265 Avg Close $6.87 Range $5.29 - $8.48

Q2 2022

Shares 13,400 Value ($000) $85 Avg Close $5.67 Range $4.59 - $7.05

Q3 2019

Shares 58,400 Value ($000) $2,141 Avg Close $39.61 Range $33.13 - $47.94

Q2 2019

Shares 153,800 Value ($000) $7,155 Avg Close $46.96 Range $39.03 - $52.99

Q1 2019

Shares 67,500 Value ($000) $2,710 Avg Close $44.86 Range $39.29 - $54.94

Q4 2018

Shares 46,700 Value ($000) $2,148 Avg Close $48.18 Range $36.06 - $60.99

Q1 2018

Shares 21,300 Value ($000) $1,541 Avg Close $73.43 Range $61.20 - $82.68

Q4 2017

Shares 24,000 Value ($000) $1,580 Avg Close $53.84 Range $42.55 - $68.60

Q3 2017

Shares 14,800 Value ($000) $742 Avg Close $48.22 Range $43.06 - $57.38

Q2 2015

Shares 63,759 Value ($000) $5,213 Avg Close $97.89 Range $72.05 - $120.96

Q1 2015

Shares 22,359 Value ($000) $2,070 Avg Close $64.53 Range $41.00 - $118.95

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,505,200	$12,969	$3.23	$2.30 - $4.13
Q3 2025	1,908,000	$5,056	$1.93	$0.95 - $2.94
Q2 2025	2,093,700	$2,061	$1.00	$0.69 - $1.46
Q1 2025	2,527,000	$3,639	$1.84	$1.42 - $2.40
Q4 2024	3,616,200	$7,956	$2.33	$1.58 - $3.94
Q3 2024	3,600,100	$5,940	$2.02	$1.60 - $2.77
Q2 2024	3,874,300	$8,601	$2.35	$1.71 - $3.40
Q1 2024	3,569,700	$9,567	$2.43	$1.65 - $3.34
Q4 2023	2,146,600	$6,418	$1.30	$0.70 - $3.28
Q3 2023	1,536,300	$1,506	$1.45	$0.85 - $1.99
Q2 2023	685,032	$952	$1.40	$1.12 - $1.84
Q1 2023	857,200	$1,363	$5.16	$1.26 - $7.41
Q4 2022	1,416,000	$8,822	$7.15	$4.88 - $8.87
Q3 2022	1,084,300	$7,265	$6.87	$5.29 - $8.48
Q2 2022	13,400	$85	$5.67	$4.59 - $7.05
Q3 2019	58,400	$2,141	$39.61	$33.13 - $47.94
Q2 2019	153,800	$7,155	$46.96	$39.03 - $52.99
Q1 2019	67,500	$2,710	$44.86	$39.29 - $54.94
Q4 2018	46,700	$2,148	$48.18	$36.06 - $60.99
Q1 2018	21,300	$1,541	$73.43	$61.20 - $82.68
Q4 2017	24,000	$1,580	$53.84	$42.55 - $68.60
Q3 2017	14,800	$742	$48.22	$43.06 - $57.38
Q2 2015	63,759	$5,213	$97.89	$72.05 - $120.96
Q1 2015	22,359	$2,070	$64.53	$41.00 - $118.95