EXELIXIS INC

Ticker: EXEL CUSIP: 30161Q104 Class: EQTY

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018

Shares 513,410 Value ($000) $11,049 Avg Close $20.68 Range $18.50 - $23.76

Q1 2018

Shares 1,162,644 Value ($000) $25,753 Avg Close $27.64 Range $21.69 - $32.20

Q4 2017

Shares 1,506,499 Value ($000) $45,798 Avg Close $26.60 Range $23.85 - $32.50

Q3 2017

Shares 2,082,012 Value ($000) $50,447 Avg Close $26.62 Range $23.18 - $29.50

Q2 2017

Shares 2,082,012 Value ($000) $51,280 Avg Close $21.16 Range $18.03 - $25.22

Q1 2017

Shares 2,603,569 Value ($000) $56,419 Avg Close $20.34 Range $14.22 - $23.49

Q4 2016

Shares 3,003,569 Value ($000) $44,783 Avg Close $14.43 Range $10.04 - $18.29

Q3 2016

Shares 4,929,494 Value ($000) $63,048 Avg Close $10.81 Range $7.81 - $15.58

Q2 2016

Shares 2,580,000 Value ($000) $20,150 Avg Close $5.76 Range $3.90 - $7.90

Q1 2016

Shares 2,580,000 Value ($000) $10,320 Avg Close $4.23 Range $3.55 - $5.85

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2018	513,410	$11,049	$20.68	$18.50 - $23.76
Q1 2018	1,162,644	$25,753	$27.64	$21.69 - $32.20
Q4 2017	1,506,499	$45,798	$26.60	$23.85 - $32.50
Q3 2017	2,082,012	$50,447	$26.62	$23.18 - $29.50
Q2 2017	2,082,012	$51,280	$21.16	$18.03 - $25.22
Q1 2017	2,603,569	$56,419	$20.34	$14.22 - $23.49
Q4 2016	3,003,569	$44,783	$14.43	$10.04 - $18.29
Q3 2016	4,929,494	$63,048	$10.81	$7.81 - $15.58
Q2 2016	2,580,000	$20,150	$5.76	$3.90 - $7.90
Q1 2016	2,580,000	$10,320	$4.23	$3.55 - $5.85