EXICURE INC

CUSIP: 30205M101 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021
Shares 421,900 Value ($000) $85 Avg Close — Range —
Q1 2021
Shares 76,132 Value ($000) $166 Avg Close — Range —
Q4 2020
Shares 15,498 Value ($000) $27 Avg Close — Range —
Q3 2020
Shares 262,316 Value ($000) $459 Avg Close — Range —
Q2 2020
Shares 259,713 Value ($000) $634 Avg Close — Range —
Q1 2020
Shares 98,200 Value ($000) $145 Avg Close — Range —