FENNEC PHARMACEUTICALS INC

Ticker: FENC CUSIP: 31447P100 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 13,000 Value ($000) $100 Avg Close $8.21 Range $7.35 - $9.92

Q1 2023

Shares 34,200 Value ($000) $285 Avg Close $9.27 Range $7.08 - $10.85

Q4 2022

Shares 55,000 Value ($000) $528 Avg Close $8.85 Range $7.35 - $10.38

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	13,000	$100	$8.21	$7.35 - $9.92
Q1 2023	34,200	$285	$9.27	$7.08 - $10.85
Q4 2022	55,000	$528	$8.85	$7.35 - $10.38