GLOBAL BLOOD THERAPEUTICS IN

CUSIP: 37890U108 Class: COMMON STOCK

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q3 2022
Shares 3,559 Value ($000) $242 Avg Close — Range —
Q4 2020
Shares 7,601 Value ($000) $329 Avg Close — Range —
Q4 2019
Shares 5,718 Value ($000) $455 Avg Close — Range —
Q1 2017
Shares 9,546 Value ($000) $352 Avg Close — Range —