GLOBAL BLOOD THERAPEUTICS IN

CUSIP: 37890U108 Class: COMMON STOCK

JGP Global Gestao de Recursos Ltda.'s Holding History (CIK: 0001536562)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 6,370 Value ($000) $337 Avg Close — Range —
Q4 2018
Shares 5,764 Value ($000) $237 Avg Close — Range —