HALOZYME THERAPEUTICS INC

Ticker: HALO CUSIP: 40637H109 Class: EQTY

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q3 2019

Shares 299,969 Value ($000) $4,653 Avg Close $16.47 Range $15.07 - $17.79

Q2 2019

Shares 299,969 Value ($000) $5,153 Avg Close $16.14 Range $14.65 - $17.43

Q1 2019

Shares 299,969 Value ($000) $4,830 Avg Close $16.20 Range $13.84 - $17.76

Q4 2018

Shares 299,969 Value ($000) $4,389 Avg Close $15.95 Range $13.24 - $18.76

Q3 2018

Shares 449,969 Value ($000) $8,176 Avg Close $17.52 Range $16.46 - $18.85

Q2 2018

Shares 1,283,929 Value ($000) $21,660 Avg Close $18.91 Range $16.74 - $20.54

Q1 2018

Shares 1,581,424 Value ($000) $30,980 Avg Close $19.37 Range $16.06 - $21.48

Q4 2017

Shares 1,581,424 Value ($000) $32,040 Avg Close $18.38 Range $16.58 - $21.13

Q3 2017

Shares 1,581,424 Value ($000) $27,469 Avg Close $13.54 Range $11.41 - $17.62

Q2 2017

Shares 1,581,424 Value ($000) $20,274 Avg Close $13.36 Range $11.51 - $15.05

Q1 2017

Shares 1,391,507 Value ($000) $18,034 Avg Close $12.64 Range $9.68 - $15.20

Q4 2016

Shares 1,391,507 Value ($000) $13,748 Avg Close $10.95 Range $8.18 - $14.38

Q3 2016

Shares 1,731,057 Value ($000) $20,911 Avg Close $10.22 Range $8.43 - $12.75

Q2 2016

Shares 1,838,057 Value ($000) $15,862 Avg Close $9.87 Range $7.70 - $12.33

Q1 2016

Shares 1,931,057 Value ($000) $18,287 Avg Close $9.41 Range $6.96 - $17.51

Q4 2015

Shares 1,931,057 Value ($000) $33,465 Avg Close $15.94 Range $12.80 - $18.65

Q3 2015

Shares 1,931,057 Value ($000) $25,934 Avg Close $20.08 Range $12.80 - $25.25

Q2 2015

Shares 1,931,057 Value ($000) $43,603 Avg Close $17.58 Range $13.91 - $22.85

Q1 2015

Shares 2,248,152 Value ($000) $32,104 Avg Close $14.42 Range $9.47 - $16.55

Q4 2014

Shares 2,776,143 Value ($000) $26,790 Avg Close $8.88 Range $7.51 - $10.00

Q3 2014

Shares 2,776,143 Value ($000) $25,263 Avg Close $9.52 Range $8.58 - $10.70

Q2 2014

Shares 2,776,143 Value ($000) $27,428 Avg Close $8.48 Range $6.88 - $12.97

Q1 2014

Shares 5,698,139 Value ($000) $72,366 Avg Close $14.84 Range $11.28 - $18.18

Q4 2013

Shares 6,297,026 Value ($000) $94,392 Avg Close $12.86 Range $9.33 - $16.36

Q3 2013

Shares 7,017,608 Value ($000) $77,474 Avg Close $8.33 Range $6.51 - $12.15

Q2 2013

Shares 6,553,150 Value ($000) $52,098 Avg Close $6.37 Range $5.03 - $8.49

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2019	299,969	$4,653	$16.47	$15.07 - $17.79
Q2 2019	299,969	$5,153	$16.14	$14.65 - $17.43
Q1 2019	299,969	$4,830	$16.20	$13.84 - $17.76
Q4 2018	299,969	$4,389	$15.95	$13.24 - $18.76
Q3 2018	449,969	$8,176	$17.52	$16.46 - $18.85
Q2 2018	1,283,929	$21,660	$18.91	$16.74 - $20.54
Q1 2018	1,581,424	$30,980	$19.37	$16.06 - $21.48
Q4 2017	1,581,424	$32,040	$18.38	$16.58 - $21.13
Q3 2017	1,581,424	$27,469	$13.54	$11.41 - $17.62
Q2 2017	1,581,424	$20,274	$13.36	$11.51 - $15.05
Q1 2017	1,391,507	$18,034	$12.64	$9.68 - $15.20
Q4 2016	1,391,507	$13,748	$10.95	$8.18 - $14.38
Q3 2016	1,731,057	$20,911	$10.22	$8.43 - $12.75
Q2 2016	1,838,057	$15,862	$9.87	$7.70 - $12.33
Q1 2016	1,931,057	$18,287	$9.41	$6.96 - $17.51
Q4 2015	1,931,057	$33,465	$15.94	$12.80 - $18.65
Q3 2015	1,931,057	$25,934	$20.08	$12.80 - $25.25
Q2 2015	1,931,057	$43,603	$17.58	$13.91 - $22.85
Q1 2015	2,248,152	$32,104	$14.42	$9.47 - $16.55
Q4 2014	2,776,143	$26,790	$8.88	$7.51 - $10.00
Q3 2014	2,776,143	$25,263	$9.52	$8.58 - $10.70
Q2 2014	2,776,143	$27,428	$8.48	$6.88 - $12.97
Q1 2014	5,698,139	$72,366	$14.84	$11.28 - $18.18
Q4 2013	6,297,026	$94,392	$12.86	$9.33 - $16.36
Q3 2013	7,017,608	$77,474	$8.33	$6.51 - $12.15
Q2 2013	6,553,150	$52,098	$6.37	$5.03 - $8.49