HERON THERAPEUTICS INC

Ticker: HRTX CUSIP: 427746102 Class: COM

Brevan Howard Capital Management LP's Holding History (CIK: 0001512857)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 35,036 Value ($000) $46 Avg Close $1.23 Range $1.00 - $1.44

Q2 2025

Shares 19,806 Value ($000) $41 Avg Close $2.04 Range $1.65 - $2.61

Q1 2025

Shares 77,541 Value ($000) $171 Avg Close $1.94 Range $1.46 - $2.68

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	35,036	$46	$1.23	$1.00 - $1.44
Q2 2025	19,806	$41	$2.04	$1.65 - $2.61
Q1 2025	77,541	$171	$1.94	$1.46 - $2.68