HERON THERAPEUTICS INC

Ticker: HRTX CUSIP: 427746102 Class: COM

Sofinnova Investments, Inc.'s Holding History (CIK: 0001631134)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022

Shares 11,060 Value ($000) $63 Avg Close $7.32 Range $4.58 - $10.40

Q4 2021

Shares 2,933,351 Value ($000) $26,781 Avg Close $10.21 Range $8.23 - $12.79

Q3 2021

Shares 2,301,179 Value ($000) $24,600 Avg Close $12.17 Range $10.10 - $16.16

Q2 2021

Shares 1,467,675 Value ($000) $22,778 Avg Close $15.91 Range $12.96 - $18.99

Q1 2020

Shares 481,608 Value ($000) $5,654 Avg Close $18.80 Range $9.60 - $24.76

Q4 2019

Shares 50,500 Value ($000) $1,187 Avg Close $22.12 Range $17.25 - $26.81

Q3 2019

Shares 103,602 Value ($000) $1,917 Avg Close $18.41 Range $15.68 - $21.80

Q2 2019

Shares 617,185 Value ($000) $11,474 Avg Close $19.98 Range $16.20 - $26.59

Q1 2019

Shares 233,651 Value ($000) $5,710 Avg Close $26.18 Range $22.87 - $28.70

Q4 2018

Shares 359,713 Value ($000) $9,331 Avg Close $27.49 Range $21.25 - $32.45

Q3 2018

Shares 295,589 Value ($000) $9,356 Avg Close $37.25 Range $29.30 - $41.55

Q2 2018

Shares 26,644 Value ($000) $1,035 Avg Close $31.84 Range $26.00 - $42.90

Q1 2018

Shares 30,133 Value ($000) $832 Avg Close $22.68 Range $17.85 - $32.70

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2022	11,060	$63	$7.32	$4.58 - $10.40
Q4 2021	2,933,351	$26,781	$10.21	$8.23 - $12.79
Q3 2021	2,301,179	$24,600	$12.17	$10.10 - $16.16
Q2 2021	1,467,675	$22,778	$15.91	$12.96 - $18.99
Q1 2020	481,608	$5,654	$18.80	$9.60 - $24.76
Q4 2019	50,500	$1,187	$22.12	$17.25 - $26.81
Q3 2019	103,602	$1,917	$18.41	$15.68 - $21.80
Q2 2019	617,185	$11,474	$19.98	$16.20 - $26.59
Q1 2019	233,651	$5,710	$26.18	$22.87 - $28.70
Q4 2018	359,713	$9,331	$27.49	$21.25 - $32.45
Q3 2018	295,589	$9,356	$37.25	$29.30 - $41.55
Q2 2018	26,644	$1,035	$31.84	$26.00 - $42.90
Q1 2018	30,133	$832	$22.68	$17.85 - $32.70