HERON THERAPEUTICS INC

Ticker: HRTX CUSIP: 427746102 Class: COM

Aigen Investment Management, LP's Holding History (CIK: 0001741224)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 12,717 Value ($000) $17 Avg Close $1.23 Range $1.00 - $1.44

Q2 2024

Shares 13,484 Value ($000) $47 Avg Close $3.07 Range $2.27 - $3.93

Q4 2021

Shares 19,818 Value ($000) $179 Avg Close $10.21 Range $8.23 - $12.79

Q4 2019

Shares 37,509 Value ($000) $881 Avg Close $22.12 Range $17.25 - $26.81

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	12,717	$17	$1.23	$1.00 - $1.44
Q2 2024	13,484	$47	$3.07	$2.27 - $3.93
Q4 2021	19,818	$179	$10.21	$8.23 - $12.79
Q4 2019	37,509	$881	$22.12	$17.25 - $26.81