HISTOGEN INC

CUSIP: 43358Y103 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022
Shares 14,600 Value ($000) $4 Avg Close — Range —
Q4 2021
Shares 29,000 Value ($000) $10 Avg Close — Range —
Q3 2021
Shares 13,400 Value ($000) $10 Avg Close — Range —