HOTH THERAPEUTICS INC

Ticker: HOTH CUSIP: 44148G204 Class: COMMON STOCK

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 17,346 Value ($000) $28 Avg Close $1.41 Range $1.14 - $2.12

Q2 2025

Shares 11,099 Value ($000) $13 Avg Close $0.98 Range $0.66 - $1.78

Q1 2025

Shares 11,247 Value ($000) $11 Avg Close $1.19 Range $0.74 - $3.80

Q4 2024

Shares 11,100 Value ($000) $8 Avg Close $0.84 Range $0.65 - $1.33

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	17,346	$28	$1.41	$1.14 - $2.12
Q2 2025	11,099	$13	$0.98	$0.66 - $1.78
Q1 2025	11,247	$11	$1.19	$0.74 - $3.80
Q4 2024	11,100	$8	$0.84	$0.65 - $1.33