HYPERION THERAPEUTICS INC

CUSIP: 44915N101 Class: COM

FIRST MANHATTAN CO. LLC.'s Holding History (CIK: 0000728083)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 1,000 Value ($000) $45 Avg Close — Range —
Q4 2014
Shares 1,000 Value ($000) $24 Avg Close — Range —
Q3 2014
Shares 1,000 Value ($000) $25 Avg Close — Range —
Q2 2014
Shares 1,000 Value ($000) $26 Avg Close — Range —
Q1 2014
Shares 1,000 Value ($000) $25 Avg Close — Range —